Sermorelin - British Dragon

Buy Sermorelin 5 mg vials by British Dragon at XSteroids. Sermorelin is the GHRH analogue research peptide - the 1-29 fragment of human growth hormone-releasing hormone - supplied by British Dragon as a 5 mg lyophilized vial that is dissolved before use. This page covers what it does, the doses on record, how a 5 mg vial calculates and how to store it.

Sermorelin was once an approved medicine and is no longer marketed in that form; sold here it is a research product and the notes below are educational.

What Sermorelin Is

Sermorelin acetate is a 29-amino-acid peptide, the shortest fully functional piece of human GHRH. It binds the GHRH receptor on the pituitary and mimics the natural signal, so the gland releases its own growth hormone instead of receiving it from outside. That is the point of the compound, and it is also why it is not the same product as an HGH injection.

Because the release runs through the body's own feedback, growth hormone comes out in pulses and somatostatin puts a ceiling on the response. Vendor texts argue that this pulse pattern is why sermorelin is described as avoiding tachyphylaxis. That claim sits with the brand rather than with a trial, and it is stated here as such.

What It Does and What Is Missing

The evidence base is diagnostic and paediatric, not cosmetic. Intravenous sermorelin at 1 mcg per kg was studied as a test for growth hormone deficiency in children and adults, and subcutaneous dosing of 30 mcg per kg nightly was used in some pre-pubertal children, with growth velocity maintained for 12 months in that group. There is no randomised trial of sermorelin in healthy adults for anti-ageing or physique goals, so the real picture is narrower than the marketing on generic peptide sites.

Reconstitution and Storage

The vial arrives as a lyophilized powder and is mixed with 1 to 2 ml of bacteriostatic water, which gives 2.5 to 5 mg per ml. Keep the powder cold and dry, do not freeze it, and once dissolved store the solution at 2-8 C and use it within about 30 days. The brand publishes this as a general rule for its peptide line rather than a line written specifically for sermorelin, so treat it as vendor guidance.

Sermorelin Dosage

Vendor materials describe 200 to 500 mcg subcutaneously once a day, taken 30 to 60 minutes before sleep on an empty stomach, with a starting point of 200 to 250 mcg and a cycle of 12 to 16 weeks followed by a 4 to 6 week break. Clinical dosing is a different animal: 1 mcg per kg intravenously for the diagnostic test, and 30 mcg per kg subcutaneously in the paediatric work. Those numbers were never meant to describe the same situation, so do not swap one for the other.

How a 5 mg Vial Calculates

With U-100 syringes, 100 units is 1 ml. Dissolved in 2 ml the vial holds 2.5 mg per ml, so 0.1 ml is 250 mcg or 10 units. Dissolved in 1 ml it holds 5 mg per ml, so 0.1 ml is 500 mcg or 20 units. On that arithmetic one 5 mg vial covers 20 days at 250 mcg a day and 10 days at 500 mcg a day.

Sermorelin vs Ipamorelin

These two are stacked constantly and they are not the same kind of compound. Sermorelin is a GHRH analogue and acts on the GHRH receptor; Ipamorelin is a ghrelin receptor agonist and acts somewhere else entirely, which is exactly why the pair is combined. The line also carries Tesamorelin, a longer GHRH analogue, and the repair peptides BPC-157, TB-500 and GHK-Cu.

Side Effects

Reported effects are dominated by injection site reactions. Across the wider GH peptide class the reviews list oedema and fluid retention, muscle and joint pain, injection site reactions, changes in blood glucose and rises in prolactin or cortisol. Sermorelin also sits on the WADA prohibited list under class S2, growth hormone-releasing hormone and its analogues, and it is banned at all times.

Why Buy Sermorelin from XSteroids?

British Dragon sermorelin comes straight from the brand catalogue with secure checkout, US domestic delivery in 3 to 6 days and international delivery in 12 to 26 days. The rest of the peptide line, including MOTS-c, sits on the British Dragon brand page.