MOTS-c - British Dragon

Buy MOTS-c 10 mg vials by British Dragon at XSteroids. MOTS-c is the mitochondrial research peptide that acts on glucose metabolism in skeletal muscle, supplied by British Dragon as a 10 mg lyophilized vial that is dissolved before use. This page covers what it is, what it is not, how far the human data goes, how a 10 mg vial calculates and how to store it.

MOTS-c has no approval anywhere and cannot be compounded; sold here it is a research product and the notes below are educational.

What MOTS-c Is

MOTS-c stands for mitochondrial open reading frame of the 12S rRNA-c. It is a 16-amino-acid peptide coded by a mitochondrial gene rather than a nuclear one, and it is described as regulating glucose metabolism in skeletal muscle. Levels rise with exercise, which is why the compound is labelled an exercise mimetic, and the research around it points to metabolic control rather than to muscle building.

What MOTS-c Is Not

Three things are worth stating plainly. It is not a steroid and not a hormone, so nothing about it runs through the androgen receptor. It is not an approved drug anywhere. And it is not a substance a pharmacy can compound: the FDA put MOTS-c in front of its Pharmacy Compounding Advisory Committee in July 2026, and the briefing document points to a lack of clinical evidence on efficacy and safety, with no basis to include it in compounded preparations.

How Far the Human Data Goes

Animal work is where the substance currently lives. In mice, MOTS-c has been linked to better physical performance, reduced obesity and a longer healthy lifespan, and the original 2015 paper described improved metabolic homeostasis with lower insulin resistance. In humans nothing is finished. Observational studies connect plasma MOTS-c levels with metabolic markers but say nothing about giving the peptide, and a 2023 review notes that no effective way to use MOTS-c in the clinic has been developed.

One trial is running. NCT07505745 is a phase 2a study in 120 adults with prediabetes and excess weight, randomised and placebo controlled, using a fixed once-daily subcutaneous dose for 12 weeks, with the change in the Matsuda index as the primary endpoint. That is a live study, not a result.

Reconstitution and Storage

There is no regulator standard for a MOTS-c vial because no label exists. Vendor guidance for research peptides is to keep the lyophilized powder at 2-8 C, or in the freezer for long storage, and once dissolved to hold the solution at 2-8 C and use it within about 28 to 30 days. Treat that as vendor guidance, since nobody has published a validated storage standard for this peptide.

How a 10 mg Vial Calculates

With a U-100 syringe, 100 units is 1 ml. Rebuilt with 1 ml the vial is 10 mg per ml, so 0.5 mg is 5 units and 1 mg is 10 units. With 2 ml it is 5 mg per ml and 1 mg becomes 20 units. With 5 ml it is 2 mg per ml and a 1 mg dose is 50 units.

Vendor protocols talk about four injections over a 20-day cycle from a 10 mg vial. No approved human dose exists, so those numbers are seller practice rather than a schedule.

MOTS-c vs the Other Research Peptides

The mechanism here is mitochondrial and nothing else in the line works that way. Tesamorelin is a GHRH analogue that cuts visceral fat through growth hormone and IGF-1, which is a different route to a related goal, and Sermorelin does the short version of the same trick. Ipamorelin comes at it from the ghrelin receptor instead. None of the three touches the mitochondrion.

Side Effects and Banned Status

No trial has measured tolerability, so the reports are what buyers describe rather than clinical findings: a racing pulse, irritation at the injection site, insomnia, local or general immune reactions and fever. Separately, MOTS-c is banned in sport permanently. WADA lists it under class S4.4, metabolic modulators, as an activator of AMPK, and an exemption is unrealistic because there is no approved therapeutic use to justify one.

Why Buy MOTS-c from XSteroids?

British Dragon MOTS-c comes straight from the brand catalogue with secure checkout, US domestic delivery in 3 to 6 days and international delivery in 12 to 26 days. The rest of the research line, including GHK-Cu and BPC-157, is on the British Dragon brand page.