Glutathione - Generic Peptides

Buy Glutathione 200 mg and 500 mg by Generic Peptides at XSteroids. Glutathione is a tripeptide of glutamic acid, cysteine and glycine, and it is the main antioxidant inside human cells. Generic Peptides supplies the reduced form as lyophilized vials of 200 mg and 500 mg. This page covers the chemistry, the pharmacokinetics that make injected glutathione so short acting, the dosing and mixing logic, and the uncomfortable evidence gap behind the skin lightening practice.

Worth saying at the top: the injectable skin lightening use that made glutathione famous in bodybuilding has very little clinical support, and one systematic review concluded that intravenous use should not be done at all. This page reports that rather than ignoring it.

What Glutathione Is and What You Are Buying

Reduced glutathione, usually written GSH, is a three amino acid peptide with a molecular mass near 307.32 g/mol. It exists in every human cell at millimolar concentrations and is regenerated from its oxidised form by glutathione reductase, a reaction that consumes NADPH. The cysteine residue is the reactive part, which is why glutathione also acts as a cysteine reservoir and as a carrier in liver detoxification reactions.

Because it is a natural molecule present in food, glutathione is often treated as harmless by definition. That reasoning fails for injections, where the substance bypasses digestion and reaches plasma directly, and it is the reason the regulatory picture below matters.

What you are buying is one vial of lyophilized reduced glutathione, listed as 200 mg or 500 mg, with no diluent in the package: bacteriostatic water is ordered separately. It is the GSH form, not a liposomal oral capsule or a cream, and the vial size sits at the scale of a hospital antioxidant infusion rather than a micro-dosed peptide.

How Glutathione Works in the Body

Antioxidant and detox roles

Glutathione is a cofactor for glutathione peroxidase, which neutralises peroxides, and for glutathione S-transferases, which conjugate drugs and toxins for excretion. It also keeps other antioxidants such as vitamins C and E in their active form. These functions are the basis of the claim that a deficiency state leaves cells exposed to oxidative stress.

Why injected glutathione disappears so fast

Published pharmacokinetics are unambiguous: after an intravenous infusion the elimination half-life of exogenous glutathione is about 14 minutes, with a volume of distribution near 176 ml per kg, and urinary excretion rises sharply within the first 90 minutes. Other work puts the figure around 10 minutes. In practice that means a bolus injection is gone from plasma long before a weekly protocol can justify itself, which is one reason researchers discuss liposomal and precursor approaches instead.

What to Expect from Injectable Glutathione

Set expectations honestly. The injected molecule has an elimination half-life of roughly 14 minutes, so a single bolus is cleared from plasma long before a weekly schedule can claim a sustained effect. For skin lightening, the 2025 systematic review found moderate support only for the topical and oral routes and just one small placebo-controlled trial of the intravenous route, with 6 of 16 responders against about 3 of 16, which is why the authors concluded that intravenous glutathione is contraindicated. Oral and topical forms are studied separately, and comparing them with an injected vial is not valid. There is no published clinical trial of injectable glutathione for skin lightening.

Glutathione Doses and Reconstitution

Mixing the 200 mg and 500 mg vials

The 200 mg vial with 2 ml of bacteriostatic water reaches 100 mg per ml, and 0.1 ml of that holds 10 mg, the 10-unit line on a U-100 insulin syringe. Five millilitres brings the 500 mg vial to the same concentration, while 10 ml dilutes it to 50 mg per ml, where 0.1 ml carries 5 mg and the 10-unit mark is unchanged. Swirl, do not shake, and refrigerate the mixed vial.

Amounts discussed in the literature

Clinical infusion studies of glutathione use hundreds of milligrams per infusion, so the 500 mg vial matches the scale of published work rather than a micro-dose peptide protocol. Supplier write-ups for research use suggest 200 to 600 mg once or twice weekly. None of these amounts is approved for self-administration, and the correct comparison for the compound is a hospital infusion protocol, not a supplement label.

Stacking Glutathione With Other Generic Peptides

Glutathione is a support compound rather than a driver. In longevity stacks it is usually paired with NAD+ 500 mg, because both molecules sit in the same redox economy. On the immune side it appears with Thymalin 50 mg and Thymosin Alpha-1 5 mg, and in metabolic stacks with 5-Amino-1MQ 50 mg, which targets the same NAD+ and methylation pathways from a different angle. For antioxidant coverage in a repair block, Epitalon 10 mg and Selank 5 mg are the usual neighbours.

Recovery and Cycle Notes for Glutathione

Glutathione has no effect on the androgen axis and requires no post-cycle therapy of its own. In bodybuilding forums it is often presented as liver protection during an oral steroid phase, but there is no dose-finding study in that setting, and the honest position is that the practice rests on antioxidant theory rather than on outcome data. The same caution applies to the widely repeated claim that injections raise intracellular glutathione stores for weeks.

Glutathione Side Effects and Legal Status

Reported effects

Local injection site reactions are the most common complaint. Reported problems with intravenous skin lightening services include skin reactions and systemic complaints, with limited published safety data on chronic use. Inhaled glutathione has been linked to bronchospasm, which shows that this molecule is not inert when it reaches the airway.

Skin lightening: the evidence gap

A 2025 systematic review found moderate support for topical and oral glutathione in melasma but only one placebo controlled trial of the intravenous route, with 6 of 16 responders against 3 of 18.7 percent, and a p value of 0.054. The authors concluded that intravenous glutathione is contraindicated because of insufficient efficacy and side effects. The Philippine FDA has stated that no published trial of injectable glutathione for skin lightening exists.

Anti-doping position

Glutathione itself is not a listed prohibited substance. The relevant rule is class M2.2, which prohibits intravenous infusions and injections of more than 100 ml in any 12 hour period except for legitimately received hospital treatment. A drip protocol therefore collides with the anti-doping rules even though the molecule is not named.

Glutathione Handling and Storage Notes

Until it is mixed, reduced glutathione is held at 2 to 8 C and out of direct light. A reconstituted vial goes back into the refrigerator as well and remains usable for 28 to 30 days; freezing the solution is not an option, and any vial that looks cloudy or has changed colour should be thrown away.

Why Buy Glutathione from XSteroids?

Buying Glutathione from Generic Peptides at XSteroids gives you the exact vial strengths listed in the catalog, 200 mg and 500 mg. Checkout is encrypted, delivery inside the United States takes 3 to 6 days, and international orders arrive in 12 to 26 days. We publish the weak spots too, including the review that recommends against intravenous use.