5-Amino-1MQ - Generic Peptides

Buy 5-Amino-1MQ 10 mg and 50 mg by Generic Peptides at XSteroids. The first thing to know is that 5-Amino-1MQ is not a peptide at all: it is a small synthetic molecule, 5-amino-1-methylquinolinium, that blocks the enzyme nicotinamide N-methyltransferase, or NNMT. Generic Peptides lists it in 10 mg and 50 mg lyophilized vials. This page explains what NNMT does, what the mouse studies actually measured, how the vials are mixed and why the human data are still missing.

Because the compound sits in peptide catalogs, buyers often assume peptide rules apply. They do not, and the dosing scale is completely different, which is why the mixing section below uses milligram strengths rather than micrograms.

What 5-Amino-1MQ Is and What You Are Buying

NNMT is a cytosolic enzyme that takes a methyl group from SAM, S-adenosylmethionine, and attaches it to nicotinamide, producing 1-methylnicotinamide and SAH. That reaction drains two things at once: the main methyl donor of the cell and a precursor of NAD+, the coenzyme behind cellular energy metabolism. Blocking NNMT is therefore a way of pushing intracellular SAM and NAD+ levels up rather than adding either molecule from outside.

5-Amino-1MQ is one of a family of methylquinolinium inhibitors built for that job. It is membrane permeable in PAMPA and Caco-2 assays and was described as highly selective: in the published work it did not inhibit related SAM-dependent methyltransferases or the enzymes of the NAD+ salvage pathway.

What you are buying is a single glass vial of lyophilized powder, listed as 10 mg or 50 mg, with no diluent included: bacteriostatic water is ordered separately. Despite the catalog position, this is a small molecule rather than a peptide, and it is not supplied as a capsule or tablet, so any oral protocol discussed online does not match this vial.

How 5-Amino-1MQ Works

The mouse data behind the hype

A 2018 study in Biochemical Pharmacology showed that methylquinolinium inhibitors lowered intracellular 1-methylnicotinamide, raised NAD+ and SAM, and suppressed lipogenesis in cultured adipocytes. In diet-induced obese mice, systemic treatment significantly reduced body weight, white adipose mass, adipocyte size and plasma total cholesterol, with no change in food intake and no observable adverse effects.

What the follow-up showed

A 2022 study in Scientific Reports used 5-Amino-1MQ at 32 mg per kg of active ingredient by daily subcutaneous injection in obese mice switched to a low-fat diet, and adiposity returned to lean values faster than with the diet change alone. The same paper notes that the compound has poor oral bioavailability in mice, which is why it was injected rather than dosed in water.

Human data

There are none. As of the sources behind this page no clinical trial of 5-Amino-1MQ in people has been published, only observational work linking higher NNMT activity to obesity and type 2 diabetes. Mouse pharmacology is not a human protocol, and the difference in scale between a mouse study and a person is large.

What to Expect from 5-Amino-1MQ Research

Be clear about the evidence level. Everything measurable comes from mice and cell cultures: reduced 1-methylnicotinamide, higher NAD+ and SAM, lower lipogenesis in adipocytes, and in diet-induced obese mice a fall in body weight, fat mass and plasma cholesterol with unchanged food intake at 32 mg per kg of active ingredient injected daily. No human trial has been published, and observational links between higher NNMT activity and obesity or type 2 diabetes do not prove that inhibiting the enzyme helps a person. The compound has poor oral bioavailability in mice, so an oral dose cannot be assumed to behave like the injected one. Treat the animal results as mechanism evidence, not as an expected outcome.

5-Amino-1MQ Doses and Reconstitution

Mixing the 10 mg and 50 mg vials

Mix the 10 mg vial with 1 ml of bacteriostatic water to reach 10 mg per ml, so 0.1 ml delivers 1 mg, matching the 10-unit mark on a U-100 insulin syringe. Two millilitres of water instead brings the strength to 5 mg per ml, and 0.1 ml then holds 500 mcg while the syringe still reads 10 units. For the 50 mg vial, use 5 ml for 10 mg per ml or 10 ml for 5 mg per ml. Swirl gently and refrigerate.

Scale warning

This is where a small molecule differs from a peptide. Research amounts discussed for this compound are measured in milligrams, not micrograms, and published mouse work used tens of milligrams per kilogram of body weight. Anyone reading supplier schedules should check the unit twice, because a microgram protocol copied from a peptide vial would be meaningless here.

Stacking 5-Amino-1MQ With Other Generic Peptides

The natural partner is NAD+ 500 mg, since both approaches aim at the same coenzyme pool, one by supplying it and one by sparing it. For the lipolytic side of a body recomposition plan, AOD 9604 5 mg and HGH Frag 176-191 5 mg are the fragments studied for fat metabolism, and AICAR 50 mg represents the opposite research angle: activating AMPK instead of manipulating NAD+. On the GLP-1 side, Semaglutide 5 mg and Tirzepatide 5 mg are the appetite based options, while Glutathione 200 mg covers the antioxidant part of the same metabolic story.

Cycle and Recovery Planning for 5-Amino-1MQ

5-Amino-1MQ is not a hormone and has no suppressive effect on the androgen axis, so no post-cycle therapy follows from using it. The only recovery note that matters is the absence of human safety data: without a published elimination profile, an interval chosen from mouse work cannot be called evidence based. Cycle lengths quoted by suppliers are conventions, not findings.

5-Amino-1MQ Side Effects and Legal Status

Reported effects

In the mouse studies, no observable adverse effects were reported at the doses used. That is a statement about mice. For humans there is no tolerance data, no interaction data and no long term safety data. Because the compound is a quaternary ammonium salt, injection site reactions are the most likely local effect.

Regulatory and anti-doping status

5-Amino-1MQ is not approved as a medicine anywhere and is not registered as a supplement. It is sold as a research chemical. It is not named on the WADA Prohibited List, but as a substance with no medical approval it can be caught by class S0, non-approved substances, so athletes should not read the missing name as permission.

5-Amino-1MQ Storage and Stability

The dry powder is held at 2 to 8 C, shielded from light. Once water is added, the vial returns to the refrigerator and its contents should be used within 28 to 30 days, with freezing avoided at every stage. A small organic molecule is generally tougher in solution than a peptide, but the maker publishes no shelf life for the mixed form.

Why Buy 5-Amino-1MQ from XSteroids?

Buying 5-Amino-1MQ from Generic Peptides at XSteroids gives you the 10 mg or 50 mg vial from a catalog that labels the compound honestly as a small molecule rather than a peptide. Payment is processed over a secure connection, US orders are delivered in 3 to 6 days, and overseas parcels take 12 to 26 days.