Thymalin - Generic Peptides

Buy Thymalin 20 mg and 50 mg by Generic Peptides at XSteroids. Thymalin is not a single synthetic peptide but a polypeptide fraction extracted from calf thymus, and its active components are two short dipeptides known as KE and EW. Generic Peptides lists it as a lyophilized vial in 20 mg and 50 mg sizes, which is larger than the 10 mg clinical vial used in the Russian medical literature. This page covers what the extract actually is, what the published data show, how each vial is mixed, the cycling logic and the honest limits of the evidence.

One framing note first: the immune and longevity claims around Thymalin come almost entirely from one research school in St. Petersburg. That work is real and published, but it has not been reproduced by independent Western trials, so nothing below should be read as a promise.

What Thymalin Is and What You Are Buying

Thymalin is a polypeptide extract of bovine thymus, registered as a medicine in Russia and studied there since the 1970s. Because it is an extract rather than a defined sequence, its exact composition varies by lot, and that is the first thing to understand when comparing it with a synthetic thymic peptide such as Thymosin Alpha-1 5 mg, which is a single 28 amino acid chain with a known formula.

Published work identifies KE (Lys-Glu) and EW (Glu-Trp) as the active dipeptides of the preparation. Both are small enough to cross the cell membrane and reach the nucleus, which is the basis of the bioregulator concept: short peptides act as signals that switch gene expression rather than as hormones that bind surface receptors.

What you are buying is one glass vial of lyophilized powder, listed as 20 mg or 50 mg, with no diluent in the box: bacteriostatic water is ordered separately and mixed on receipt. This is the research presentation of a compound that reaches clinics in Russia as an injectable medicine, not a tablet or a pre-filled syringe.

How Thymalin Works at the Cell Level

The dipeptide mechanism

Molecular docking work published in 2023 showed that EW prefers the GGAG sequence of B-form DNA while KE prefers the curved GCGC sequence, and that their likely targets are genes for AKT1 and AKT2, the ACE2 and CYSLTR1 genes for EW and CHUK for KE. In an inflammation model using human peripheral blood mononuclear cells, Thymalin and its dipeptides lowered the synthesis of IL-1beta, IL-6 and TNF-alpha by 1.4 to 6.0 times.

Clinical and longevity data

In severe COVID-19 in older patients, a Russian group gave Thymalin 10 mg in 2 ml of saline intramuscularly once daily for 10 days and reported normalisation of lymphocyte, monocyte, leukocyte and NK cell counts. The longevity data come from a 2003 report on 266 people aged 60 and over followed for six to eight years: mortality was 2.0 to 2.1 times lower in the Thymalin group, 2.5 times lower with Thymalin plus a pineal peptide, and 4.1 times lower in a subgroup treated annually for six years. Those are the numbers the authors published, and they have not been independently replicated.

What to Expect in Thymalin Research

Honesty first: the immune and longevity numbers behind Thymalin come from one Russian research school and have not been independently reproduced. In the severe COVID-19 study in older patients, 10 mg intramuscularly daily for 10 days was reported to normalise lymphocyte, monocyte, leukocyte and NK counts alongside standard care. In the 2003 longevity report on 266 people aged 60 and over, mortality was 2.0 to 2.1 times lower in the Thymalin group, 2.5 times lower with Thymalin plus a pineal peptide and 4.1 times lower in a subgroup treated annually for six years. Those are the authors' figures, not an independently confirmed outcome.

Thymalin Doses and Reconstitution

Mixing a 20 mg vial

A 20 mg vial mixed with 2 ml of bacteriostatic water comes to 10 mg per ml, so a tenth of a millilitre carries 1 mg, which is the 10-unit mark on a U-100 insulin syringe. Doubling the water to 4 ml halves the strength to 5 mg per ml, so the same 10 units then hold 500 mcg. Never shake the vial; rotate it gently and keep the mixed material refrigerated.

Mixing the 50 mg vial

Add 5 ml of water to the 50 mg vial for 10 mg per ml, or 2 ml for 25 mg per ml where 0.1 ml holds 2.5 mg. Both sizes are research quantities, so a single vial covers many weeks of any protocol described in the literature.

Amounts used in the literature

Russian clinical papers describe 5 to 10 mg intramuscularly once daily for 5 to 10 days, and the COVID-19 study used exactly 10 mg daily for 10 days. At 10 mg per day the 20 mg vial covers two days and the 50 mg vial five days. None of these amounts is approved by the FDA or the EMA, and the 20 mg and 50 mg vials are research products rather than the registered 10 mg prescription form.

Stacking Thymalin With Other Generic Peptides

The classic pairing in the Russian literature is with a pineal peptide, which is why Epitalon 10 mg sits next to Thymalin in the longevity line. On the immune side, Thymosin Alpha-1 is the synthetic counterpart and Glutathione 500 mg covers the antioxidant part of the same story. For general cellular energy, NAD+ 500 mg is the compound most often mentioned alongside thymic extracts, and Selank 30 mg is the neuro-immune option when sleep and stress are part of the plan.

Recovery and Cycle Breaks on Thymalin

Thymalin leaves the androgen axis untouched, so no post-cycle therapy is required after it. The published courses are short, 5 to 10 days, followed by a break of weeks or months, and one long-term study dosed annually for six consecutive years. That structure, a short pulse with a long gap, is the practical summary for anyone reading the literature. Because there is no human pharmacokinetic profile, injection intervals are convention rather than measured kinetics.

Thymalin Side Effects and Legal Status

Reported tolerability

In the small published studies the preparation was described as well tolerated, with no serious adverse events singled out. Injection site reactions are the expected local effect of any intramuscular peptide, and because the product is an animal tissue extract rather than a defined peptide, allergic reactions are a theoretical concern that a data sheet cannot rule out.

Regulatory and anti-doping status

Thymalin is registered as a medicine in Russia but has no FDA or EMA approval, and the vials sold here are research products. It is not named individually on the WADA Prohibited List, so there is no named ban to quote; as a substance with no approval in the United States or the European Union it can fall under class S0. Anyone subject to testing should treat that ambiguity as a risk rather than as permission.

Thymalin Storage and Stability

Keep Thymalin as a powder between 2 and 8 C and away from light; a freezer is worth using only if the vial will be held for months. After mixing, the solution stays usable for 28 to 30 days in the same 2 to 8 C range and should be discarded at the end of that window. A reconstituted peptide must never be frozen, and a cloudy solution must never be used.

Why Buy Thymalin from XSteroids?

Buying Thymalin from Generic Peptides at XSteroids means a 20 mg or 50 mg lyophilized vial, clear pack data on this page and the same shipping terms as the rest of the catalog: orders inside the United States arrive in 3 to 6 days and international parcels in 12 to 26 days, with every payment handled over a secure connection. The evidence behind the compound is narrow and mostly Russian, and we say so plainly instead of dressing it up.