Ipamorelin - Kalpa Pharmaceuticals

Buy Ipamorelin 5 mg by Kalpa Pharmaceuticals at XSteroids. This growth hormone secretagogue ships from Kalpa as one vial of lyophilised powder for bench work. The page details what you are buying: the molecule and its ghrelin-receptor target, the human pharmacokinetic studies, the selectivity data, the mixing arithmetic, and the anti-doping picture.

The position goes first. Ipamorelin was dropped during development, no medicines authority has licensed it, and the vial is offered as a research item. The content that follows is neither a dosing schedule nor medical guidance.

What the Ipamorelin 5 mg Vial Is and What You Are Buying

Ipamorelin is a synthetic pentapeptide written Aib-His-D-2-Nal-D-Phe-Lys-NH2 and coded NNC 26-0161. It was derived from GHRP-1 and behaves as a selective agonist at the ghrelin receptor, the family also called growth hormone secretagogues. That receptor is the switch it uses to prompt the pituitary.

Each pack holds a single sealed glass vial of white powder at 5 mg, drawn up with bacteriostatic water bought separately. Kalpa prints the mass on the label, and no filler list or batch potency report appears here, so the contents rest on the manufacturer like any research vial.

How Ipamorelin Works at the Ghrelin Receptor

By binding the ghrelin receptor, ipamorelin pushes the pituitary to release its own growth hormone instead of supplying hormone from outside. The human volunteer pharmacology is well described: the terminal half-life is about two hours and the growth hormone peak lands near 0.67 hours before falling exponentially. Five infusion rates between 4.21 and 140.45 nmol per kg over fifteen minutes were studied, behaving proportionally with dose, a clearance near 0.078 L per hour per kg, a distribution volume of 0.22 L per kg and a half-maximal growth hormone concentration around 214 nmol per L.

Selectivity is what sets it apart from older compounds. Profiling in rats and pigs found no effect on FSH, LH, prolactin or TSH, and unlike GHRP-2 and GHRP-6 it did not lift ACTH or cortisol even at doses above two hundred times its ED50 for growth hormone. In animals it also raised body mass, and in rats it produced longitudinal bone growth.

What to Expect from Ipamorelin in Human Data

The human dataset is real but small, and it is pharmacokinetic rather than outcome-based. The formulation was developed by Novo Nordisk and later taken forward by Helsinn Therapeutics for a phase II study in postoperative ileus, which failed to show benefit and was discontinued. There is no licensed medicine form of ipamorelin, and today it trades as a research peptide without a label dose.

That gap matters. The volunteer studies describe hormone release and clearance precisely, but they do not establish any clinical benefit, so vendor language about recovery, fat loss or physique change is not supported by the human record. A study block is a research construct, not a treatment plan.

Mixing the Ipamorelin 5 mg Vial for a U-100 Barrel

Concentration is the fill weight shared across the water you introduce. A 5 mg fill sits at 5000 mcg per ml across one millilitre, 2500 mcg per ml across two millilitres, and 1000 mcg per ml across five millilitres. A U-100 syringe marks hundredths of a millilitre, so every 0.1 ml drawn equals ten marks on the barrel, carrying 500, 250 or 100 mcg respectively. At 300 mcg a day a single vial stretches to roughly sixteen days, at 600 mcg to about eight, and at 900 mcg to some five and a half.

Add the water down the side of the vial, swirl it gently rather than shaking, and note the strength per millilitre and the mixing date on the tube before it goes cold, so later draws stay repeatable.

Stacking the Ipamorelin Vial With a GHRH Peptide

Ipamorelin works through the ghrelin receptor, so it is normally discussed with a GHRH analogue that feeds a different pituitary input. The natural partner in this line is Sermorelin 5 mg, a GHRH(1-29) peptide that triggers the same output down a separate route, which is why the pair is studied together rather than as substitutes.

On the wider shelf the vial shares space with the repair items BPC 157 2 mg and TB 500 5 mg, which touch unrelated pathways, and with the prescription Kalpatropin growth hormone product. Every one of them arrives dry and shares the same bacteriostatic water.

Recovery Notes for a Secretagogue Block

A secretagogue leaves the androgen axis alone, so it creates no shutdown needing a post-cycle plan. What it may do is push the endocrine system while it is running, which makes any recovery question about returning to baseline rather than restarting testosterone production.

Where the vial is studied alongside an anabolic run, that run still owns its recovery plan, and a peptide block changes nothing on that shelf. With no label to follow, there is no guidance on how long a block should run, and the honest position is that the researcher decides.

Ipamorelin Side Effects and WADA Standing

Vendor descriptions call the profile clean with respect to appetite, cortisol and prolactin, which matches the selectivity work. A 2026 review of unregulated growth hormone peptides, however, lists endocrine and metabolic shifts, fluid retention, musculoskeletal symptoms and injection site reactions across the class. There is no formal human safety dataset for the compound at research amounts, and a research peptide sits outside pharmaceutical quality control.

In sport the position is clear. WADA's 2026 list names ipamorelin as an example inside class S2, the growth hormone secretagogue section, and the prohibition is permanent, with no in-competition allowance and no exemption to apply for.

Handling and Storing the Ipamorelin Vial

Refrigerate the sealed powder at 2 to 8 C, shaded from light. For brief periods it is fine at controlled room temperature between 15 and 25 C; freezing the powder is what to avoid, because ice damages the peptide. Kept cold, the dry vial is stable for a long time.

Once water is added the vial lives in the fridge at 2 to 8 C and is best finished inside a month, the familiar 28 to 30 day peptide range. Do not refreeze a mixed vial, and do not keep one that has clouded or dropped visible particles. Store it out of reach of children.

Why Buy Ipamorelin from XSteroids?

This 5 mg vial appears in the Kalpa Pharmaceuticals catalog at XSteroids next to the GHRH peptide and the diluent it is studied with, so the bench ships together. Checkout is encrypted; orders inside the United States generally land in 3 to 6 days while overseas delivery runs 12 to 26 days. The related cards below show what is normally bought with it.