Adipotide - Dragon Pharma

Buy Adipotide 10 mg by Dragon Pharma at XSteroids. Adipotide is the most radical idea in fat-loss research: instead of changing metabolism, it destroys the blood supply that feeds fat tissue. Dragon Pharma supplies it as a 10 mg lyophilized vial. This guide covers the mechanism, the animal data, adipotide dosage practice and why the programme was shelved.

Adipotide is not approved anywhere and clinical development has stopped, so the information below is educational only.

About Adipotide by Dragon Pharma

Adipotide is the trade name of prohibitin-targeting peptide 1, also written prohibitin-TP01 or TP01. Chemically it is a peptidomimetic with the sequence CKGGRAKDC-GG-D(KLAKLAK)2 - a targeting domain joined to a cell-killing domain, which is the whole trick of the design.

The targeting half binds two receptors, ANXA2 and prohibitin, that are characteristic of the blood vessels feeding white adipose tissue. The killing half then does what it does to cells it has been delivered to.

How Adipotide Works

Mechanism of Action

Adipotide is an experimental proapoptotic drug. It reaches the vessels that supply adipose tissue with blood, causes those vessels to shrink, and the fat cells that depended on them undergo apoptosis. The fat is not mobilised - it is starved and then dismantled at the cellular level.

The Animal Data

In mice and in rhesus monkeys, that mechanism produced rapid weight loss. The monkey work is the reason the compound got attention, because a primate response is a much stronger signal than a rodent one, and it included improved insulin resistance. What does not exist is a human weight-loss dataset.

Adipotide Dosage and Research Status

Dosing

There is no approved dose, and no human dose at all. Research discussions are extrapolated from animal work in micrograms per kilogram, which is a weak basis for a compound this potent. The 10 mg vial is reconstituted with bacteriostatic water, and the dilution ratio decides the units per injection.

Why It Stopped

Adipotide carries an investigational status, and as of 2019 clinical development has been discontinued. The reason follows from the mechanism: a drug that works by ablating blood vessels lives or dies on how precisely it hits its target, so the margin between the fat vasculature and everything else is the entire safety question. Closing the programme means that margin was not good enough to continue.

Adipotide Side Effects

Because there is no human dataset, there is no side effect profile to quote - and that absence is itself the relevant information. The plausible risks are the mechanism itself: unintended effects on blood vessels and tissue outside the target, plus all the unknowns of a proapoptotic agent. If a reader sees this described as a simple fat-loss peptide, the description is doing a lot of work that the evidence does not support.

Adipotide vs AOD-9604 and Tesamorelin

All three are sold as fat-loss compounds and they could not be more different. AOD-9604 is a lipolytic HGH fragment that reached human trials, produced a small effect and was abandoned. Adipotide is a targeted apoptosis agent with striking animal data and no human programme. Tesamorelin is the only one of the three with an approval and a randomised human trial behind its fat-reduction claim. The growth-axis compounds, from CJC-1295 DAC to Sermorelin, work indirectly through GH and IGF-1 rather than touching fat vasculature at all. If evidence matters, the ranking is unambiguous; if mechanism is what interests you, adipotide is the most unusual molecule on this list.

Storage Instructions

Store the lyophilized vial in a cool, dry place away from direct light before reconstitution. After mixing with bacteriostatic water, keep the solution refrigerated and use it within the recommended period for peptide solutions. Keep vials out of the reach of children.

Why Buy Adipotide from XSteroids?

At XSteroids you buy the Dragon Pharma Adipotide vials directly from the brand catalog, with secure checkout, US domestic shipping in 3 to 6 days and international delivery in 12 to 26 days. Browse the full range on the Dragon Pharma brand page to complete your research protocol.