Tesamorelin - Dragon Pharma

Buy Tesamorelin 5 mg by Dragon Pharma at XSteroids. Tesamorelin is the rare compound in this category that is a genuine prescription medicine: a synthetic GHRH analogue approved as Egrifta. Dragon Pharma supplies it as a 5 mg lyophilized vial. This guide covers the approved indication, how it works, tesamorelin dosage in medical and research settings, and the side effects that come with the drug.

What is approved is the Egrifta product for a specific indication; a research vial is not that medicine, so the information below is educational only.

About Tesamorelin by Dragon Pharma

Tesamorelin is a synthetic form of growth hormone-releasing hormone. Structurally it contains all 44 amino acids of human GHRH with a trans-3-hexenoic acid group attached at the N-terminus, a modification that protects the peptide from enzymatic cleavage and is the reason it works long enough to be a practical drug.

It was approved in 2010 for HIV-associated lipodystrophy and is produced by Theratechnologies. It carries the ATC code H01AC06 and is prescription-only in the United States - a status almost nothing else in this catalog shares. The distinction matters: the approved medicine has a defined dose and indication, while the vial sold for research use does not.

How Tesamorelin Works

Mechanism of Action

Tesamorelin stimulates the synthesis and release of endogenous growth hormone, which in turn raises insulin-like growth factor 1. The resulting signalling regulates body composition through a mix of anabolic and lipolytic mechanisms, and that lipolytic side is what the approved indication targets - reducing excess visceral abdominal fat in patients with HIV-associated lipodystrophy.

Half-Life and Duration of Action

Its bioavailability is 4% or less and its elimination half-life is only 26 to 38 minutes, so it is given by subcutaneous injection and clears quickly. That short window is why the medical product is dosed daily rather than weekly, and it is the main practical difference from CJC-1295 DAC, which lasts six to eight days.

Tesamorelin Dosage and Research Use

Dosing

In medicine, tesamorelin is a fixed daily subcutaneous dose within a prescription protocol with monitoring. A research vial changes the arithmetic: the 5 mg of lyophilized powder is reconstituted with bacteriostatic water, and the ratio determines how many units on an insulin syringe equal a given amount. There is no clinical dose defined for self-directed use.

Reconstitution

Mix the powder with bacteriostatic water, aiming the stream at the vial wall rather than the powder, then swirl gently instead of shaking. Label the vial with the date, keep it refrigerated, and treat a punctured multi-dose vial as usable for 28 days after the first puncture. Its short half-life means it is usually dosed close to the natural GH pulse.

Tesamorelin Side Effects and Contraindications

The documented adverse effects are injection site erythema and itching, peripheral oedema and diarrhoea; with frequent use, joint, arm and leg pain can appear as body fat is depleted. Tesamorelin is also contraindicated when the hypothalamic-pituitary axis is disrupted - pituitary tumours, prior head irradiation or hypopituitarism - and in pregnancy. Those are clinical constraints attached to the approved drug, and they are the most concrete safety information available for any GHRH analogue in this catalog.

Tesamorelin vs Sermorelin, CJC-1295 and Ipamorelin

All four act on the growth hormone axis from two directions. Sermorelin is the short-acting GHRH fragment that was once approved and then discontinued; tesamorelin is the currently approved GHRH analogue; CJC-1295 DAC is the long-acting research option. On the ghrelin side, Ipamorelin is the selective peptide with no cortisol or appetite effect, and it is also sold combined with tesamorelin as Ipamorelin and Tesamorelin.

Storage Instructions

Store the lyophilized vial in a cool, dry place away from direct light before reconstitution. After mixing with bacteriostatic water, keep the solution refrigerated and use it within the recommended period for peptide solutions. Keep vials out of the reach of children.

Why Buy Tesamorelin from XSteroids?

At XSteroids you buy the Dragon Pharma Tesamorelin vials directly from the brand catalog, with secure checkout, US domestic shipping in 3 to 6 days and international delivery in 12 to 26 days. Browse the full range on the Dragon Pharma brand page to complete your research protocol.