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Dragon Pharma
AOD-9604 - Dragon Pharma
$70.00
- Active Substance: AOD-9604 (HGH Fragment 176-191)
- Classification: Lipolytic HGH Fragment (Research)
- Dose: 5 mg per vial
- Pack Size: Lyophilized vial for reconstitution
- Half-Life: Not established in humans
- Common Use: Fat Metabolism Research
- Manufacturer: Dragon Pharma
Shipping:
International
U.S. Domestic
Estimated Delivery: 12-26 Days (International), 3-6 Days (United States)
Return within 45 Days of purchase. Duties & taxes are non-refundable.
Buy AOD-9604 5 mg by Dragon Pharma at XSteroids. AOD-9604 is the fat-loss peptide with the clearest failure on its record: it went through human trials, produced a modest result and was abandoned. Dragon Pharma supplies it as a 5 mg lyophilized vial. This guide covers the chemistry, the trial record and the direct question of whether it works.
AOD-9604 was never approved and development stopped, so the information below is educational only.
About AOD-9604 by Dragon Pharma
AOD-9604 is an orally active, lipolytic peptide made of 16 amino acids. It is a fragment of human growth hormone, residues 176 to 191, with a tyrosine replacing the phenylalanine at the N-terminal end - hence its other name, HGH Fragment 176-191. It is the C-terminal region of growth hormone that carries the fat-mobilising activity.
The idea was appealing: keep the lipolytic part of growth hormone and drop the rest, for fat loss without growth or IGF-1 effects.
How AOD-9604 Works
Mechanism of Action
In mice, AOD-9604 appears to enhance lipolysis by upregulating beta-3 adrenergic receptors, and beta-3 knockout mice do not respond at all. That is a clean mechanistic story.
No IGF-1 Stimulation
Initial human trials showed it retains the lipolytic properties of growth hormone without stimulating IGF-1 production - a genuine distinction from growth hormone itself, and the main argument in its favour.
Does AOD-9604 Work: The Trial Record
The Numbers
In a 12-week randomised clinical trial, subjects taking AOD-9604 lost on average 1.8 kg more than those on placebo - a real but small difference. Development was halted after poor efficacy in a 24-week trial and terminated in 2007: later studies simply failed to show a sufficient lipolytic effect.
What That Means
This is the honest summary: AOD-9604 reached human testing, produced a modest short-term result, then failed to hold up over a longer duration - which is why it never became a medicine. Anyone reading that it is a powerful fat-burner is reading marketing, not trial data. That said, it remains popular in research settings precisely because it does not touch IGF-1, which keeps it separate from growth-axis compounds such as Tesamorelin, Sermorelin and IGF-1 LR3.
AOD-9604 Dosage and Handling
Dosing
No clinical dose exists. Practice works in hundreds of micrograms daily, taken from trial protocols rather than any approved schedule. The 5 mg vial is reconstituted with bacteriostatic water, so the dilution ratio sets the units per dose. It has been studied by injection and orally, unusual for a peptide.
Reconstitution
Mix the powder with bacteriostatic water, aiming the stream at the vial wall rather than the powder, then swirl gently instead of shaking. Label the vial with the date, keep it refrigerated, and treat a punctured multi-dose vial as usable for 28 days after the first puncture.
AOD-9604 Side Effects and Banned Status
Tolerability in the human studies was acceptable, consistent with a fragment that avoids IGF-1 stimulation - the side effect profile was not why the drug failed, efficacy was. There is no long-term safety dataset, and the current supply is not a regulated product. One further detail: despite its disappointing efficacy, AOD-9604 is banned in sport and tested in competition, so athletes cannot treat it as a harmless loophole.
AOD-9604 vs Tesamorelin and Other Fat-Loss Compounds
If the goal is visceral fat, Tesamorelin is the only compound here with an approved indication and randomised evidence for that claim. AOD-9604 has the more attractive mechanism and the weaker result. On the growth side, CJC-1295 DAC and Ipamorelin raise GH and IGF-1 indirectly - exactly what AOD-9604 was designed to avoid.
Storage Instructions
Store the lyophilized vial in a cool, dry place away from direct light before reconstitution. After mixing with bacteriostatic water, keep the solution refrigerated and use it within the recommended period for peptide solutions. Keep vials out of the reach of children.
Why Buy AOD-9604 from XSteroids?
At XSteroids you buy the Dragon Pharma AOD-9604 vials directly from the brand catalog, with secure checkout, US domestic shipping in 3 to 6 days and international delivery in 12 to 26 days. Browse the full range on the Dragon Pharma brand page to complete your research protocol.
Frequently Asked Questions
What is AOD-9604?
AOD-9604 is a 16-amino-acid lipolytic fragment of human growth hormone, corresponding to residues 176 to 191 with a tyrosine at the N-terminal end. It is also sold as HGH Fragment 176-191. Dragon Pharma supplies it as a 5 mg lyophilized vial for research use.
How does AOD-9604 work?
In mice it enhances lipolysis by upregulating beta-3 adrenergic receptors, and beta-3 knockout mice do not respond to it. Initial human trials found it keeps the lipolytic effect of growth hormone without stimulating IGF-1 production, unlike growth hormone itself in that respect.
AOD-9604 dosage: how much is used?
There is no approved dose. Practice works in hundreds of micrograms daily, taken from trial protocols rather than an approved schedule, and the reconstitution ratio of the 5 mg vial sets the units per dose, so careful measurement of each dose matters.
Does AOD-9604 actually work?
The trial record is modest at best. In a 12-week randomised trial subjects lost about 1.8 kg more than placebo, and development was halted after poor efficacy in a later 24-week trial and the programme was terminated in 2007 after later studies failed to show a sufficient effect.
Does AOD-9604 raise IGF-1 or growth hormone?
No, and that is its defining feature. Initial human studies showed it retains the lipolytic effect of growth hormone without increasing IGF-1, which separates it entirely from growth-axis compounds such as CJC-1295 or Tesamorelin. That is the whole selling point of the fragment.
Is AOD-9604 banned in sport?
Yes. Despite its limited efficacy in trials, AOD-9604 is banned for athletes and is tested for in competition, so it is treated as a prohibited substance regardless of how well it performed in trials. Athletes cannot use it as a loophole.
Where to buy AOD-9604 online?
You can buy AOD-9604 5 mg vials by Dragon Pharma online at XSteroids. The store offers secure checkout, US domestic shipping in 3 to 6 days and international delivery in 12 to 26 days. Add the vial to your cart on this page. All orders ship with tracking.
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