Testolone (RAD 140) - Zyvex Pharmaceuticals

Buy Testolone (RAD 140) by Zyvex at XSteroids. The pack on this page holds the non-steroidal selective androgen receptor modulator that published work lists as vosilasarm, supplied by Zyvex as a laboratory reference. The sections below set out what the pack is, how a SARM signal differs from a steroid signal, the receptor affinity figures, how long the molecule circulates, what human trials have recorded, which support items are usually kept beside it, how the natural axis is checked afterwards and how the pack is stored.

RAD 140 is a research compound and this material is labelled for laboratory work, so every figure here comes from published trials, animal studies and case reports rather than from a treatment programme.

What the Zyvex Testolone Pack Is and What You Are Buying

One sealed pack of RAD-140, also written rad140, filed in the literature under the international name vosilasarm and the development code EP0062. On the grey market the same molecule travels as Testolone and Testalone, which are trade labels rather than chemical names. The pack carries a Zyvex label with a batch code and an expiry date, and the strength printed there is a label claim: no independent assay of these lots has appeared.

The class matters more than the nickname. RAD-140 is a SARM, a selective androgen receptor modulator, a synthetic molecule built to bind the androgen receptor without a steroid skeleton. Reading it as a gentler steroid is the commonest mistake made about this group.

How a Selective Androgen Receptor Modulator Works

The androgen receptor is the target testosterone and dihydrotestosterone already use, and RAD-140 binds it firmly: published affinity work places its Ki near 7 nM, against roughly 29 nM for testosterone and 10 nM for dihydrotestosterone. Selectivity against other steroid receptors is the design aim, since a molecule that leans on muscle and bone while sparing prostate and skin would separate the useful effect from the rest.

That separation remains a research goal rather than a settled result. Development began at Radius Health and continues at Ellipses Pharma, and the surviving programme is in androgen receptor positive, oestrogen receptor negative, HER2 negative advanced breast cancer; work on sarcopenia, osteoporosis and cachexia was dropped. The half-life is long, quoted at 45 to 60 hours, which supports once-daily use.

What to Expect from a RAD 140 Run

Suppression of the user's own testosterone belongs at the top of the list. In male cynomolgus monkeys the compound cut testosterone by approximately half and moved triglycerides, LDL and HDL, and that animal finding is the firmest signal available on the hormonal axis. Human trials were run in patients with metastatic breast cancer, so their adverse events describe a treated and unwell population rather than healthy users.

In those early clinical reports vomiting and dehydration each appeared in about 27 percent of participants, with constipation, appetite loss and weight loss recorded at the same rate. Falls in SHBG were universal, prostate specific antigen rose in roughly 80 percent, and liver enzymes climbed in half the group or more. Size and strength are what the gym audience expects, and they are exactly what no controlled study of healthy men has measured.

Two features separate a SARM cycle from a steroid cycle in the way it is monitored. The first is that no aromatase inhibitor is normally needed unless the stack contains testosterone, because a SARM does not itself become estradiol. The second is that the compound leaves no intermediate metabolite to read, so the only evidence of what is happening sits in the hormone panel and the liver enzymes.

Dosing RAD 140 in the Published Literature

Trial work used 50 to 150 mg a day, with a maximum tolerated dose reported at 100 mg a day, and those numbers belong to oncology patients rather than to a physique protocol. Community totals run lower and vary widely, which is one reason little can be said with confidence about an effective amount in a healthy person.

Reading the pack instead of a forum

Where the printed strength is known, that figure decides how the daily amount is built; where it is not, the honest answer is that the user is guessing. A half-life of two days or more means the level accumulates over the first week and does not vanish overnight if an occasion is missed.

Stacking Testolone With Support Compounds

Because the compound suppresses the axis without supplying testosterone, a base is the usual structural choice, and Testosterone Esters from Zyvex is the card that covers it. Oestrogen control belongs in the plan for a different reason: a suppressed axis alters the ratio between oestradiol and testosterone, and Arimidex (anastrozole) is the item Zyvex keeps for that job.

The recovery drawer holds Nolvadex (tamoxifen) and Clomid (clomiphene). Repair research sits alongside them: BPC 157 and TB-500 cover soft tissue work, while Ligandrol (LGD 4033) and Ostarine (MK 2866) are the neighbouring SARMs used for comparison.

Recovery and Testing After Testolone

Recovery starts from a suppressed axis, so Clomid or Nolvadex is community practice rather than a documented protocol: no trial has published a restart schedule after RAD-140 in healthy men. Timing is guided by blood work, not by the calendar on a forum.

Long-term human data do not exist for this compound. What can be measured is a panel before the run and again after it: total and free testosterone, luteinising hormone, follicle stimulating hormone, oestradiol, a lipid profile and liver enzymes, with prostate specific antigen alongside if the user's doctor considers it relevant.

RAD 140 Side Effects and Precautions

On record from trials are falls in SHBG, rises in prostate specific antigen, higher liver transaminases and bilirubin, and gastrointestinal upset. In non-medical use the literature also describes liver toxicity and a single myocarditis case, and monkey data show lipid movement alongside the testosterone fall.

Two further cautions belong here. Analyses of grey market SARM products repeatedly find that the contents do not match the label, so a user may not be taking RAD-140 at all. In tested sport the compound sits in WADA class S1, other anabolic agents, and is prohibited at all times.

Storage Instructions

The factory wrapper wants a dry shelf at room temperature, clear of sunshine, radiators and steamy rooms, and somewhere children or visitors cannot pick anything up by accident. Tablets gain nothing from refrigeration and a freezer degrades them. Note the lot number and the expiry before the first unit is taken, and bin the pack if it has been opened or shows a changed appearance.

Why Buy Testolone (RAD 140) from XSteroids?

The Zyvex catalog keeps this pack next to the base, the ancillary items and the repair research a study shelf normally wants, so one order covers the list. Parcels are packed without branding and collected by the courier the same working day; addresses inside the United States usually see delivery in three to six days, and orders crossing a border in twelve to twenty-six. The cards underneath list the products most often bought with it.