GW 501516 (Cardarine) - Dragon Pharma

Buy Cardarine 20 mg tablets by Dragon Pharma at XSteroids. Cardarine, also coded GW 501516 or GW1516, is the endurance compound that gets grouped with the SARMs even though it is nothing of the kind - it is a PPAR-delta agonist, and it was abandoned in development for a reason worth knowing. Dragon Pharma supplies it as 20 mg tablets, 100 per pack. This guide covers the pharmacology, the animal cancer findings, cardarine dosage practice and the doping status.

GW 501516 was never approved and development was discontinued after animal testing raised a cancer signal, so the information below is educational only.

About Cardarine (GW 501516) by Dragon Pharma

GW 501516 is a PPAR-delta receptor agonist, invented in the 1990s through a collaboration between Ligand Pharmaceuticals and GlaxoSmithKline. It entered clinical development as a candidate for metabolic and cardiovascular disease, and it is not a SARM, not a steroid and not an androgen - a distinction that matters, because its risks and its effects belong to a completely different receptor system.

Development stopped in 2007. At the time the reason was not disclosed; it later emerged that the drug caused cancer to develop rapidly in several organs in animal testing, at doses of 3 mg per kilogram per day in mice and rats.

How Cardarine Works

PPAR-Delta Activation

PPAR-delta regulates fatty acid oxidation and energy metabolism, and activating it shifts muscle toward burning fat. That is the pharmacology behind the endurance effects - and it is also why the compound was studied for metabolic disease rather than for muscle growth.

The Endurance Finding and the Black Market

In 2007, research showed that high doses of GW501516 dramatically improved physical performance in mice. The work was covered widely in the mainstream press, which turned a failed drug candidate into a black-market product used by athletes as a doping agent. That is the entire commercial story of this compound.

Cardarine Dosage and Cycle Practice

Dosing

With no approved dose and no established human half-life in the cited sources, all dosage figures for cardarine come from user practice rather than trials - typically 10 to 20 mg per day, which is why the tablet here is 20 mg. The usual approach is to start at the lower end and run short windows, but that is convention, not evidence.

What the Labels Do Not Tell You

The dose that produced cancer in rodents was expressed in milligrams per kilogram of body weight, which for a small animal translates into a far higher exposure than a typical human dose. That comparison is often used to argue the finding away, but the toxicology was serious enough that a major pharmaceutical company walked away from the compound.

Cardarine Side Effects and Safety

The defining safety fact is the animal cancer signal at 3 mg/kg/day across multiple organs, which is why the drug was abandoned and why the World Anti-Doping Agency has issued repeated warnings that GW 501516 is not safe. Beyond that, human safety data is limited, and the compound is sold unregulated, so product purity is a separate unknown. Anyone weighing it against better documented compounds should note that Ostarine and LGD 4033 at least have clinical trials to argue about.

How Cardarine Compares to the Rest of This Category

It does not belong with the androgens at all. Ostarine, LGD 4033 and S 23 act on the androgen receptor; YK 11 is the steroidal oddity of that group; MK 677 works through the ghrelin receptor and growth hormone. Cardarine is a metabolic modulator with no hormonal mechanism, which is why its side effect list looks nothing like the others.

Storage Instructions

Store the tablets at room temperature in a dry place, away from direct light and moisture. Keep the pack sealed until use and always store it out of the reach of children.

Why Buy Cardarine from XSteroids?

At XSteroids you buy the Dragon Pharma Cardarine tablets directly from the brand catalog, with secure checkout, US domestic shipping in 3 to 6 days and international delivery in 12 to 26 days. Browse the full range on the Dragon Pharma brand page to complete your research protocol.