LGD 4033 (Ligandrol) - Dragon Pharma

Buy LGD 4033 (Ligandrol) 15 mg tablets by Dragon Pharma at XSteroids. LGD-4033 is a nonsteroidal selective androgen receptor modulator, a SARM rather than a steroid, and it is one of the most studied compounds in its class. Dragon Pharma supplies it as 15 mg tablets, 100 per pack. This guide covers what the research actually shows, how dosing in trials compares with the way it is used outside them, and the safety picture.

LGD-4033 is not approved for any medical use, and the information below is educational only.

About LGD 4033 (Ligandrol) by Dragon Pharma

LGD-4033, also coded VK5211 and sold outside pharmacies as Ligandrol, is a selective androgen receptor modulator. It is not a steroid: the molecule is nonsteroidal and binds the androgen receptor as an agonist, activating the same target that testosterone and DHT act on, but through a different structure and with different tissue selectivity.

It was developed for muscle wasting, including hip fracture recovery, and also studied for cachexia, hypogonadism and osteoporosis. Development was discontinued, and as of 2023 it is not approved for any medical use.

How LGD 4033 Works

Mechanism of Action

As an androgen receptor agonist, LGD-4033 drives the same transcriptional programme that androgens do, which is why it increases lean mass and strength in trials. Its half-life is 24 to 36 hours, which supports once-daily dosing. Pharmacokinetic work in healthy men showed dose-proportional exposure: area under the curve at day 21 was 19 ng·day/mL at 0.1 mg per day, 85 at 0.3 mg per day and 238 at 1 mg per day.

What the Trials Showed

In a phase 1 trial in 76 healthy young men, 1 mg per day increased lean body mass by 1.2 kg after three weeks. The same research found reductions in total and free testosterone, FSH, SHBG, HDL cholesterol and triglycerides, while LH, total cholesterol, LDL and PSA were unaffected - LGD-4033 is not hormonally neutral.

LGD 4033 Dosage: Research vs Real-World Use

Doses Studied

Clinical work used single doses from 0.1 to 22 mg, and repeated doses of 0.1 to 2 mg per day for three to twelve weeks. Those are the numbers with any human data behind them.

Doses Used Outside Trials

Products sold online are frequently taken at 5 to 10 mg per day, several times above the repeated-dose research range, and the adverse effects of non-medical use at those levels have not been characterised. The 15 mg tablet supplied here is above the studied range, which is worth understanding before assuming trial data applies to it.

LGD 4033 Side Effects and Hormonal Impact

Suppression of natural testosterone and FSH is the documented effect, so libido, mood and recovery can suffer, and a recovery plan with Nolvadex, Clomid or HCG plus blood work is standard. The HDL drop matters for cardiovascular risk, and the FDA has warned that SARMs can be linked to serious events including heart attack and stroke.

LGD 4033 and Anti-Doping Rules

SARMs are prohibited in sport, and LGD-4033 has produced a long list of suspensions across the NBA, swimming, athletics and canoeing. Athletes should treat any SARM as a banned substance.

Where LGD 4033 Fits in a Cycle

It is usually run as an oral lean-mass component rather than a base, and because it suppresses natural production a testosterone base is what keeps levels stable, and compounds such as Proviron are used by some for libido support. Blood work before, during and after is the only way to see what the compound is actually doing.

Storage Instructions

Store the tablets at room temperature in a dry place, away from direct light and moisture. Keep the pack sealed until use and always store it out of the reach of children.

Why Buy LGD 4033 from XSteroids?

At XSteroids you buy the Dragon Pharma LGD 4033 tablets directly from the brand catalog, with secure checkout, US domestic shipping in 3 to 6 days and international delivery in 12 to 26 days. Browse the full range on the Dragon Pharma brand page to complete your research protocol.