TB 500 - Axiolabs

Buy TB 500 5 mg by Axiolabs at XSteroids. TB 500 is a synthetic fragment of thymosin beta-4, the actin-binding protein found in almost every human cell, supplied as a lyophilized 5 mg vial. Unlike a local repair peptide, it is described as working through the whole body, so a single subcutaneous injection is not aimed at the injury itself. This page covers the chemistry, the mechanism, how a 5 mg vial is mixed, the research protocol, stacking, storage and legal status.

Two honest limits come first. TB 500 has never been tested in humans as a fragment, and its half-life is not established. Everything about dosing below is taken from research and supplier write-ups rather than from a label.

About TB 500 by Axiolabs

TB 500 is the acetylated heptapeptide Ac-LKKTETQ, a fragment of amino acids 17 to 23 of the 43 amino acid protein thymosin beta-4. Its molecular formula is C38H68N10O14. The parent protein is encoded by the TMSB4X gene and carries a molecular mass of about 4921 g/mol, so the fragment is roughly a sixth of the whole protein.

Axiolabs supplies the fragment as a lyophilized powder in a 5 mg vial that is mixed with bacteriostatic water. Some vendor pages describe the peptide as an acylation product of seven amino acids and others as a 17 amino acid fragment; the acetylated heptapeptide description matches the scientific literature and is the one used here.

How TB 500 Works

Thymosin beta-4 binds G-actin through the LKKTET motif, the segment that TB 500 reproduces. That binding regulates actin polymerisation, which in turn affects cell movement and migration. The protein also acts outside the cell, where it has been linked with tissue regeneration through pathways other than actin.

Supplier descriptions list actin binding and cell motility, angiogenesis, lower pro-inflammatory cytokines, greater collagen synthesis and keratinocyte migration as the working mechanisms. The protein itself has clinical data in one narrow area: a Phase III trial of thymosin beta-4 eye drops in neurotrophic keratopathy reported complete healing in 6 of 10 treated patients against 1 of 8 on placebo, which was a trend rather than a clean win, and a separate European Phase III missed its primary endpoint. None of that data applies to the injected fragment.

TB 500 Dosage and Reconstitution

Mixing a 5 mg vial

Add 2 ml of bacteriostatic water for 2.5 mg/ml, or 2500 mcg/ml, so 0.1 ml holds 250 mcg, equal to 10 units on a U-100 syringe. With 1 ml of water the concentration becomes 5 mg/ml and 0.1 ml holds 500 mcg. Swirl, never shake, and store the mixed vial at 2 to 8 C.

The research protocol

Supplier write-ups describe a loading phase of 2.0 to 2.5 mg twice a week for the first four weeks, which is 4 to 5 mg weekly, followed by maintenance of 2.0 to 2.5 mg once a week. Cycles run six to eight weeks followed by a break of similar length. On that schedule a 5 mg vial lasts about one week of loading or two to three weeks of maintenance.

How to Stack TB 500

TB 500 is usually paired with BPC 157 5 mg, the local member of the repair family, and with GHK-CU 50 mg when collagen is the focus. Together they cover the three angles most often discussed in research: systemic, local and skin.

On a steroid cycle the base stays in place, for example Testaplex Testosterone or AxoTropin HGH, since growth hormone is also involved in connective tissue turnover. Peptides of this type are an addition to a plan, not a substitute for one.

Recovery and Post-Cycle Support With TB 500

TB 500 does not suppress natural testosterone and does not require post-cycle therapy. If it sits inside a bigger cycle, the recovery plan concerns the anabolic part: Arimiplex 1 mg or Exeplex 25 mg for estrogen control while on, then Tamoxiplex 20 mg or Clomiplex 50 mg afterwards.

Supplier guidance says the first one to two weeks usually bring less pain and inflammation, with tissue changes over three to six weeks. That is a vendor description rather than trial data, so treat the timeline as an expectation to verify, not a promise.

TB 500 Side Effects and Precautions

What is known

There is no human safety data for the fragment. For the parent protein in eye drop form, a Phase III study reported no serious adverse events. The reference literature notes that high levels of thymosin beta-4 have been associated with tumour development, which is the most serious caution in this file.

Banned status and legal position

Thymosin beta-4 and its derivatives are named directly in WADA class S2 and are prohibited at all times. In several countries the peptide is classed as a prescription medicine while being practically unavailable by prescription, and it has a history as a racing industry substance.

General precautions

This material is for adult men, is not medical advice and is not for anyone with an active or previous cancer diagnosis. Use a fresh needle for every injection and keep vials out of reach of children.

Storing and Handling TB 500

Keep the lyophilized powder cool and dry, away from light: controlled room temperature of 15 to 25 C or the refrigerator at 2 to 8 C, and never freeze the powder. After mixing, store at 2 to 8 C and use within 30 days, avoid freeze-thaw cycles and discard a solution that turns cloudy.

Why Buy TB 500 from XSteroids?

At XSteroids you buy TB 500 directly from the Axiolabs brand catalog, with secure checkout, US domestic shipping in 3 to 6 days and international delivery in 12 to 26 days. The 5 mg vial is listed on this page, and the related products below complete the repair line and the on-cycle support around it.