GHRP-6 - Dragon Pharma

Buy GHRP-6 10 mg by Dragon Pharma at XSteroids. GHRP-6 is the original growth hormone-releasing hexapeptide - a met-enkephalin analogue that has no opioid activity at all but is a potent stimulator of growth hormone release. Dragon Pharma supplies it as a 10 mg lyophilized vial. This guide covers the pharmacology, ghrp-6 dosage practice, the appetite effect it is known for and how it compares with the newer secretagogues.

GHRP-6 has never been approved for medical use, so the information below is educational only.

About GHRP-6 by Dragon Pharma

GHRP-6, also coded SKF-110679, belongs to a family of synthetic met-enkephalin analogues built with unnatural D-amino acids. They were developed specifically for growth hormone-releasing activity, which is why they are called growth hormone secretagogues. The name enkephalin is misleading here: the compounds lack opioid activity entirely, yet they stimulate GH release powerfully.

They also differ fundamentally from growth hormone-releasing hormone. There is no sequence relation between them, and GHRP-6 works through a completely different receptor - the GH secretagogue receptor, now better known as the ghrelin receptor. Its sequence is L-histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-Lysinamide.

How GHRP-6 Works

Mechanism of Action

By activating the ghrelin receptor in the pituitary and hypothalamus, GHRP-6 triggers GH release through a pathway separate from GHRH. That separation is the reason secretagogues are paired with GHRH analogues such as CJC-1295 in research protocols: two receptors, two signals, one response.

Half-Life and Clearance Time

GHRP-6 has almost no oral bioavailability - under 1% - and an elimination half-life of about 2.5 hours, so it is an injectable peptide with a short window of action. The 10 mg vial is the standard research format, and the reconstitution ratio determines how many units on an insulin syringe equal a given dose.

GHRP-6 Dosage and the Appetite Effect

Dosing

Because the half-life is measured in hours, GHRP-6 is dosed close to the effect window, typically in small amounts once or twice daily with a pre-sleep injection timed to natural GH release. That pattern is conventional practice rather than a clinical protocol, since there is no approved dose.

Hunger

Among the GHRP peptides, GHRP-6 has the strongest reputation for driving hunger. That reputation comes from user experience rather than from a documented appetite study of GHRP-6 itself, so it should be treated as a practical observation - but it is widely consistent, and anyone running it during a cut should plan around it rather than be surprised by it. It also stimulates the corticotropic axis, unlike Ipamorelin.

GHRP-6 vs GHRP-2 and Ipamorelin

All three are ghrelin-type secretagogues, and the differences are about selectivity and history. GHRP-2 is the one that became an approved diagnostic in Japan. Ipamorelin is the most selective, with no ACTH or cortisol stimulation. GHRP-6 is the oldest of the group, the least selective of the three on the corticotropic axis, and the one most associated with appetite. Research logs often pair them with CJC-1295 without DAC or with Hexarelin, a related short-acting compound.

GHRP-6 Side Effects and Regulatory Status

Beyond GH release, the documented class effects include corticotropic stimulation, while the hunger effect is the most reported practical consequence. GHRP-6 has no ATC code and no approval anywhere; it exists as a research chemical. GH secretagogues are restricted in sport under anti-doping rules, and injecting any peptide carries the usual risks of sterile technique and product purity.

Storage Instructions

Store the lyophilized vial in a cool, dry place away from direct light before reconstitution. After mixing with bacteriostatic water, keep the solution refrigerated and use it within the recommended period for peptide solutions. Keep vials out of the reach of children.

Why Buy GHRP-6 from XSteroids?

At XSteroids you buy the Dragon Pharma GHRP-6 vials directly from the brand catalog, with secure checkout, US domestic shipping in 3 to 6 days and international delivery in 12 to 26 days. Browse the full range on the Dragon Pharma brand page to complete your research protocol.